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My interests and competences lie in developing and applying state-of-the-art models and computational techniques to obtain new insights into the fundamental physics of soft-condensed matter. This class of materials is essentially everything that is intermediate between elastic solids and viscous liquids. Typical for soft-matter is the emergence of mesoscopic structures, and it is the dynamics of these mesoscopic structures which produces the exotic properties of these materials Using the simulation data, I want to learn how to improve state-of-the art theories describing and experiments done on these systems. This approach creates strong scientific synergies.
My Ph.D. was a computational study of self-assembled block-copolymer micelles. The methods I developed remain the state-of-the-art for the analysis of experimental scattering data from such systems. As a post-doc and assistant professor, I used computational techniques to study the molecular origin of viscoelasticity in polymer materials, and the molecular response to deformation of these materials. The Science paper and two Physical Review Letters, that I have authored or coauthored remain state-of-the art in the field. At present, I'm developing new methodologies for studying DNA hybridization dynamics in conjunction with soft-condensed matter and self-assembly. Some avenues of this research is DNA directed self-assembly, DNA induced interactions between soft-matter systems, and DNA computation. See the videos below for examples
My contract at FLinT is expected to expire around 1/1 2013, so if you find my work interesting, let me know.
1. "Simulation of migration and coalescence of metal inclusions in homogeneous and isotropic media". C. Svaneborg, S. Steenstrup, and K.K. Bourdelle. Nucl. Inst. Meth. B 142, 89 (1998).
2. "A Monte Carlo study on the effect of excluded volume interactions on the scattering from block copolymer micelles". C. Svaneborg and J.S. Pedersen. J. Chem. Phys. 112, 9661 (2000).
3. "Block Copolymer micelle coronas as quasi two-dimensional dilute or semi-dilute polymer solutions". C. Svaneborg and J.S. Pedersen. Phys. Rev. E (rapid comm.) 63, 10802 (2001).
4. "Form factors of block copolymer micelles with excluded volume interactions of the corona chains determined by Monte Carlo simulations". C. Svaneborg and J.S. Pedersen. Macromolecules 35, 1028-1037 (2002).
5. "Scattering from block copolymer micelles". J.S. Pedersen and C. Svaneborg. Curr. Opinion in Colloid and Interface Science 7, 158-166 (2002).
6. "A small-angle neutron and X-ray contrast variation scattering study of the structure of block copolymer micelles: Corona shape and excluded volume interactions". J.S. Pedersen, C. Svaneborg, K. Almdalm I.W. Hamley, and R.N. Young. Macromolecules 36, 416-433 (2003)
7. "Rheology and Microscopic Topology of Entangled Polymeric Liquids". R. Everaers, S.K. Sukumaran, G.S. Grest, C. Svaneborg, A. Sivasubramanian, and K. Kremer. Science 303, 823-826 (2004)
8. "Monte Carlo simulations and analysis of scattering from neutral and polyelectrolyte polymer and polymer-like systems". C. Svaneborg and J.S. Pedersen. Current Opinion in Colloid and Interface Science 8, 507-514 (2004).
9. "Strain-Dependent Localization, Microscopic Deformations, and Macroscopic Normal Tensions in Model Polymer Networks". C. Svaneborg, G.S. Grest, and R. Everaers. Phys. Rev. Lett. 93, 257801 (2004)
10. "Disorder effects on the strain response of model polymer networks". C. Svaneborg, G.S. Grest, and R. Everaers. Polymer 46, 4283, (2005).
11. "Scattering from polymer networks under elongational strain". C. Svaneborg, G.S. Grest, and R. Everaers. Europhysics Lett. 72, 760 (2005)
12. "Permanent Set of Crosslinking Networks: Comparison of Theory with Molecular Dynamics Simulations". D. R. Rottach, J. G. Curro, J. Budzien, G. S. Grest, C. Svaneborg and R. Everaers. Macromolecules 39, 5521-5530 (2006).
13. "Molecular Dynamics Simulations of Polymer Networks Undergoing Sequential Cross-Linking and Scission Reactions". D. R. Rottach, J. G. Curro, J. Budzien, G. S. Grest, C. Svaneborg and R. Everaers. Macromolecules 40, 131-139 (2007).
14. "Connectivity and Entanglement Stress Contributions in Strained Polymer Networks". C. Svaneborg, R. Everaers, G.S. Grest, and J.G. Curro. Macromolecules 41, 4920-4928 (2008).
15. "Microphase separation in cross-linked polymer blends: Efficient replica RPA post-processing of simulation data for homopolymer networks" A.V. Klopper, C. Svaneborg, and R. Everaers. Eur. Phys. J. E. 28, 89-96 (2009).
16. "Stress Relaxation in Entangled Polymer Melts". J.-X. Hou, C. Svaneborg, R. Everaers, and G.S. Grest. Phys. Rev. Lett. 105, 068301 (2010)
17. "A formalism for scattering of complex composite structures. I. Applications to branched structures of asymmetric sub-units". C. Svaneborg and J.S. Pedersen. J. Chem. Phys. 136, 104105 (2012)
18. "LAMMPS Framework for Dynamic Bonding an Application Modeling DNA". C. Svaneborg. 2012. (In Print)
19. "A formalism for scattering of complex composite structures 2. Distributed reference points". C. Svaneborg and J.S. Pedersen. (Accepted) http://arxiv.org/abs/1108.1141
20. "DNA Self-Assembly and Computation Studied with a Coarse-grained Dynamic Bonded Model". C. Svaneborg, H. Fellermann, S. Rasmussen. Submitted to the proceedings for the DNA18 conference to appear in Lecture Notes for Computer Science (LNCS). http://arxiv.org/abs/1204.0733
Below are some videos of the kind of science I'm currently working on.
I use NAMD to perform simulations of single and double stranded DNA at various conditions. By calculating the centres of mass of the nucleosides (green spheres), we can use the simulations to learn about the interaction potentials (potentials of mean force) that should be used in one bead per nucleoside coarse-grained DNA models. The video below is a 40 bp long poly-AT strand at T=300K.
By crafting 4 different types of 3-armed single strand complexes with the right complementary DNA sequences, these can be made to self-assemble into well-defined structures such as a tetrahedron..
What happens if we increase the concentration of the complexes? A gel is formed.
Simulation of oil-surfactant-water mixture with excess surfactant.
Simulation of oil-surfactant-water mixture with excess oil.
The simulations below are of a number of DNA labelled oil droplets. The only difference is that in the first simulation DNA tags hybridize to form a double stranded bridge between the two droplets. In the latter simulation, I have reversed the direction of one sequence. Hence, the hybridization is tip-to-tether on both strands, this induces fast fusion between the two droplets.